(Banner will apear here)

Beautiful Kabbalah Jewelry Judaicawebstore.com
Font Size:

An injection that melts fat holds out promise for the obese

The cost to treat obesity in the United States alone is expected to rise from $325 billion in 2014 to $555 billion per year by 2025.

Raziel Therapeutics wants to be the Botox for obesity.

Image depicting before and after weight loss (image by Asanagi - Own work, CC0)

Whereas an injection of Botox smooths out wrinkles, this Jerusalem medical startup is developing an injection that doesn’t just smooth, but literally melts away fat cells. Unlike Botox, though, Raziel’s fat-burning approach has the potential to do a lot more than simply make you look better.

A third of the world’s population will be overweight or obese in less than a decade.

It’s no secret that obesity has become a worldwide epidemic. The cost to treat obesity in the United States alone is expected to rise from $325 billion in 2014 to $555 billion per year by 2025. The World Obesity Federation predicts there will be 2.7 billion overweight and obese adults by that time. Put more starkly: A third of the world’s population will be overweight or obese in less than a decade.

The United States already reached that point in 2014. But even developing countries like Egypt are predicted to jump to similar obesity levels in the same time period if nothing changes.

Raziel Therapeutics may be a small company today but it has big ambitions as it eyes tackling the obesity challenge head-on. “There’s no medication today for obesity that works well and will make the world healthier,” the company’s CEO, Alon Bloomenfeld, tells ISRAEL21c.

Raziel’s drug does two things when injected. “First it removes the fat cells themselves. Then it postpones the proliferation of new fat cells,” Bloomenfeld explains. Raziel’s medication works by generating heat to use up some of the free fatty acid that’s produced by fat cells in the body, which in turn reduces fat tissue.

Results from Raziel’s first US clinical trial ... showed a 30-50% reduction in subcutaneous fat at the treated site after a single injection.

Like Botox, Raziel’s injections target specific areas in the body – it’s not a pill that acts generally, Bloomenfeld explains. And here’s another overlap: the treatment only lasts for a limited period of time. Bloomenfeld estimates that time as six to nine months, although he says they’ll know more after Phase IIa FDA testing, which is scheduled to start later this year.

“No drug lasts forever,” Bloomenfeld points out. “The body finds ways to recover.” So you’ll need to go back to your doctor regularly for new shots. That’s one more similarity with Botox: Bloomenfeld expects that the injection eventually will be available in physicians’ offices.

   This article was originally published by Israel21c. Click here to continue reading the full article. 

 

Brian Blum | Israel21C

Back To The Top